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🦠 Microbiology · Method

Microbial Culture

Culture and propagate microorganisms
🎯 Difficulty ★☆☆ Easy Duration About 1–2 days 🎯 Use Grow, propagate and maintain bacteria/fungi for identification, experiments and preservation
📖 Principle
Grow microbes to target phase in nutrient/suitable pH medium under controlled temperature, oxygen and time
Below are 4 steps. Open each to see how to do it and add products to your shared list.

📋 Workflow

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1

Medium preparation

1 h
Prepare agar or broth medium, autoclave and pour plates or aliquot
💡 Tip Choose medium per microbe type
⚠️ Caution Sterilize thoroughly to avoid contamination
🧪 Materials for this step (click to shop by spec/brand)
2

Inoculation and culture

1–2 days
Inoculate colonies with loop, culture at suitable temperature (e.g. 37°C) and oxygen condition
💡 Tip Anaerobes need anaerobic jar/chamber
⚠️ Caution Sterile technique prevents cross-contamination
🧪 Materials for this step (click to shop by spec/brand)
3

Growth monitoring and purification

1 h
Monitor OD or count, streak plates to purify single colonies
💡 Tip Single colonies confirm purity
⚠️ Caution Full streaking yields isolated colonies
🧪 Materials for this step (click to shop by spec/brand)
4

Stock preservation

30 min
Add glycerol to make cryostock, store at -80°C for long-term preservation
💡 Tip Glycerol final ~15-25%
⚠️ Caution Label strain and date
🧪 Materials for this step (click to shop by spec/brand)

⚠️ 5 Common Beginner Mistakes

  • Wrong medium/pH for target microbe
  • Poor aseptic technique causes contamination
  • Anaerobes exposed to oxygen fail to grow
  • Wrong temperature/time
  • Missing label causes strain confusion

❓ FAQ

+How to confirm pure culture?
Isolate uniform single colonies; verify by Gram stain or 16S sequencing.
+Why match oxygen conditions?
Aerobes, facultative and anaerobes differ in oxygen tolerance and supply needs.
+How to preserve long-term?
Store in glycerol at -80°C or lyophilize; avoid repeated passaging to prevent mutations.

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Data authenticity: Product categories from JW Supply Chain standard taxonomy; method→step→product connected. Last updated: 2026-08-23 · v3.0