📋 Workflow
Full workflow, products add-to-cart directly1
Model establishment and grouping
1–3 weeksEstablish tumor model etc., randomize animals reaching tumor criteria into groups
💡 Tip Randomize/blind to reduce bias
⚠️ Caution Verify group baseline uniformity
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2
Dosing scheme design
1 daySet vehicle control, multi-dose and positive control groups, define route and frequency
💡 Tip Multi-dose for dose-response
⚠️ Caution Consistent vehicle and volume
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3
Dosing and monitoring
2–6 weeksAdminister per schedule, periodically measure tumor, body weight and relevant endpoints
💡 Tip Regular tumor volume measurement
⚠️ Caution Monitor toxicity and body weight
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4
Endpoint and data analysis
1 weekEuthanize, collect tumor/tissue, measure tumor weight, inhibition rate and biomarkers, run statistics
💡 Tip Compute tumor growth inhibition (TGI)
⚠️ Caution Rigorous stats, integrate safety
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⚠️ 5 Common Beginner Mistakes
- ① Uneven tumor impairs group comparison
- ② Wrong dose/route
- ③ Inconsistent vehicle/volume biases
- ④ Irregular monitoring incomparable
- ⑤ Ignoring safety overestimates efficacy
❓ FAQ
+What is tumor growth inhibition?
Percent inhibition of tumor volume/weight vs control, reflecting antitumor efficacy.
+How to set positive control?
Use a clinically relevant or class-standard validated drug to benchmark model/efficacy.
+How to balance efficacy and toxicity?
Combine dose tolerance, body weight and histopathology to assess the therapeutic window.