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GC

Volatile separation & quant
🎯 Difficulty ★★☆ Medium Duration About 2–3 h 🎯 Use Analysis of volatile organics, residual solvents and low-boiling compounds
📖 Principle
Vaporized sample is carried by carrier gas through the column for separation and detection
Below are 5 steps. Open each to see how to do it and add products to your shared list.

📋 Workflow

Full workflow, products add-to-cart directly
1

Carrier gas & column install

20 min
Install the capillary column to the detector and purge carrier gas for leak check
💡 Tip Do not overtighten column nuts
⚠️ Caution Ensure carrier gas purity before use
🧪 Materials for this step (click to shop by spec/brand)
2

Standard & sample prep

30 min
Dilute standards and samples with solvent; derivative if needed
💡 Tip Internal standard quantitation is more robust
⚠️ Caution Store volatile samples at low temperature
🧪 Materials for this step (click to shop by spec/brand)
3

Temperature program

20 min
Set initial temperature, ramp rate and final temperature to achieve separation
💡 Tip Gradual ramping improves peak shape and resolution
⚠️ Caution Do not exceed column max temperature
🧪 Materials for this step (click to shop by spec/brand)
4

Injection & detection

30 min
Inject via micro-syringe or headspace; detect with FID or MS
💡 Tip Headspace suits residual solvent analysis
⚠️ Caution Avoid air bubbles in the syringe
🧪 Materials for this step (click to shop by spec/brand)
5

Quant & data

30 min
Integrate peak areas and calculate concentration by calibration or internal standard
💡 Tip Use internal standard to correct injection errors
⚠️ Caution Run system suitability tests regularly
🧪 Materials for this step (click to shop by spec/brand)

⚠️ 5 Common Beginner Mistakes

  • Septum bleed causing ghost peaks
  • Dirty liner causing adsorption/tailing
  • Fast ramp reducing resolution
  • Volatile loss lowering quantitation
  • Excess injection causing overload

❓ FAQ

+What samples suit GC?
Vaporizable, low-boiling, thermally stable compounds.
+FID or MS?
Use FID for routine quantitation; MS for identification/high sensitivity.
+Why peak tailing?
Usually liner/column inlet contamination or active site adsorption.

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Data authenticity: Product categories from JW Supply Chain standard taxonomy; method→step→product connected. Last updated: 2026-08-23 · v3.0